
By Obrien
ISBN-10: 0824706366
ISBN-13: 9780824706364
This authoritative reference offers the newest study at the position of chemokines, chemokine receptors, and genetic variability within the susceptibility, prevention, and therapy of HIV-1-exploring new healing thoughts for more advantageous remedy of HIV-1 contaminated sufferers via blockading chemokine receptor expression. With contributions from pro specialists within the box, Chemokine Receptors and AIDS info ·the function of chemokine receptors in HIV-1 an infection and pathogenesis ·the identity and position of the CCR5-D32 allele in HIV an infection ·potential novel the way to deal with HIV-1 an infection by means of blocking off or down-regulating the CCR5 and CXCR4 HIV-1 coreceptors ·strategies utilizing monoclonal antibodies, small molecules, and ribosymes ·and extra! delivering greater than 1200 present references, Chemokine Receptors and AIDS is a vital reference for infectious illness experts, epidemiologists, virologists, immunologists, pharmacologists, medicinal chemists and biochemists, microbiologists, and clinical scholars in those disciplines.
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Roos, 1. Clark-Lewis, M. Baggiolini, and B. Moser. 1998. B cell-attracting chemokine I, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLRl/CXCR5. J Exp Med 187(4):65560. 38. N. M. H. G. T. Williams. 1998. A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-I. Nature 391 :799. 39. L. G. Cyster. 1998. Epstein-Barr virus-induced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts naive T cells and activated B cells.
M. Farber, TJ. R. B. Pert. 1999. Upregulation of RANTES in psoriatic keratinocytes: a possible pathogenic mechanism for psoriasis. Acta Derm. Venereol. 79:9. 115. , G. Sun, and U. Mrowietz. 1996. The chemotactic activity of Tlymphocytes in response to interleukin 8 is significantly decreased in patients with psoriasis and atopic dermatitis. Dermatol. 5:334. Copyrighted Material Chemokines and Chemokine Receptors 29 116. , AD. N. M. Carter. 1988. Detection of a gamma interferon-induced protein IP-I 0 in psoriatic plaques.
Renzi, S. A. Garcia-Zepada, Z. Allakhverdi, O. D. Rothenberg, AD. Luster, and Q. Hamid. 1997. Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation. lmmunol. 159:4593. 110. S. Robinson, Q. Meng, J. Rottman, R. Kennedy, OJ. R. L. S. R. J. Williams, and AB. Kay. 1997. Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co- localization of eotaxin mRNA to bronchial epithelial and endothelial cells.
Chemokine Receptors and AIDS (Infectious Disease and Therapy) by Obrien
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