This authoritative reference offers the newest study at the position of chemokines, chemokine receptors, and genetic variability within the susceptibility, prevention, and therapy of HIV-1-exploring new healing thoughts for more advantageous remedy of HIV-1 contaminated sufferers via blockading chemokine receptor expression. With contributions from pro specialists within the box, Chemokine Receptors and AIDS info ·the function of chemokine receptors in HIV-1 an infection and pathogenesis ·the identity and position of the CCR5-D32 allele in HIV an infection ·potential novel the way to deal with HIV-1 an infection by means of blocking off or down-regulating the CCR5 and CXCR4 HIV-1 coreceptors ·strategies utilizing monoclonal antibodies, small molecules, and ribosymes ·and extra! delivering greater than 1200 present references, Chemokine Receptors and AIDS is a vital reference for infectious illness experts, epidemiologists, virologists, immunologists, pharmacologists, medicinal chemists and biochemists, microbiologists, and clinical scholars in those disciplines.
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Renzi, S. A. Garcia-Zepada, Z. Allakhverdi, O. D. Rothenberg, AD. Luster, and Q. Hamid. 1997. Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation. lmmunol. 159:4593. 110. S. Robinson, Q. Meng, J. Rottman, R. Kennedy, OJ. R. L. S. R. J. Williams, and AB. Kay. 1997. Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co- localization of eotaxin mRNA to bronchial epithelial and endothelial cells.
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