By J.S. Brimacombe
Carbohydrate Chemistry offers evaluate insurance of all courses correct to the chemistry of monosaccharides and oligosaccharides in a given 12 months. the quantity of study during this box showing within the natural chemical literature is expanding as a result stronger value of the topic, specifically in parts of medicinal chemistry and biology. In no a part of the sphere is that this extra obvious than within the synthesis of oligosaccharides required via scientists operating in glycobiology. Clycomedicinal chemistry and its reliance on carbohydrate synthesis is now rather well tested, for instance, by way of the guidance of particular carbohydrate- dependent antigens, specially cancer-specific oligosaccharides and glycoconjugates. assurance of themes akin to nucleosides, amino-sugars, alditols and cyclitols additionally covers a lot learn of relevance to organic and medicinal chemistry. each one quantity of the sequence brings jointly references to all released paintings in given components of the topic and serves as a finished database for the energetic study chemist. expert Periodical reviews supply systematic and particular assessment assurance in significant parts of chemical study. Compiled by way of groups of best professionals within the appropriate topic components, the sequence creates a distinct carrier for the lively examine chemist, with ordinary, in-depth money owed of growth specifically fields of chemistry. topic insurance inside of varied volumes of a given name is the same and booklet is on an annual or biennial foundation.
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Additional info for Carbohydrate Chemistry: v. 8
L16 At elevated temperatures in the presence of oxygen, D-glucose was liberated following oxidation of the D-glucitol residue. To a lesser extent, the D-glucose moiety was oxidized and D-glucitol liberated in a consecutive reaction. Under the conditions of the experiment, D-glucose was decomposed to a complex mixture of products. ll* At lower temperatures, loss of methanol occurred during inter- and intramolecular condensations, resulting in the formation of glycans and/or 1,6-anhydrohexoses. At higher temperatures, fragmentation of the transglycosylation products occurred.
Bolker, Canad. J. , 1974, 52, 888. Y. Kamiya and S. Takemura, Chern. and Pharm. Bull. (Japan), 1974, 22, 201. V. G. Mairanovskii, N. F. Loginova, A. M. Ponomarev, and A. Ya. Veinberg, Electrolchimiya, 1974, 10, 172 (Chem. , 1974, 80, 108 770s). S. Jacobsen and C. Pedersen, Actu Chem. Scand. (B), 1974, 28, 866. 39 40 Carbohydrate Chemistry ring in methyl 2,3:4,6-di-O-benzylidene-ol-~-mannopyranoside with trityl tetrafluoroborate furnished the D-mannopyranoside 2-benzoate (with water) and methyl 2-O-benzoyl-4,6-O-benzylidene-3-bromo-3-deoxy-ol-~-altropyranos~de (with tetraethylammonium However, this type of reactivity was not shown by 1,2-O-benzylidene acetals fused to either pyranose or furanose rings.
Silica-gel chromatography of the thioacetates (88) and (89) led to acetyl migration from S-3 to 0 - 5 and -6, respectively, whereas the corresponding aa4 226 C. G. Casinovi, M. Framondino, G . Randazzo, and F. , 1974,36, 67. K. Capek, J. Stanck, and J. Jary, Coll. Czech. Chem. , 1974, 39, 2694. E. E. Lee, A. Bruzzi, E. O'Brien, and P. S. , 1974, 35, 103. 233 227 228 228 230 231 232 233 R. L. Whistler, A. K. M. Anisuzzaman, and J. C. , 1973, 31, 237. J. M. Ballard, L. Hough, and A. C. , 1974, 34, 184.
Carbohydrate Chemistry: v. 8 by J.S. Brimacombe