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Read e-book online Calcium signalling: Approaches and Findings in the Heart and PDF

5 April 2018 adminHematology

By Lars Kaestner

ISBN-10: 3642346162

ISBN-13: 9783642346163

ISBN-10: 3642346170

ISBN-13: 9783642346170

The ebook combines basic thoughts and strategies to enquire calcium signalling in cells starting from molecular biology techniques to manipulation of calcium in residing cells. the point of interest inside of those tools in at the huge variety of fluorescence imaging expertise, particularly on optical sectioning ideas and speedy snapshot acquisition. as well as those common guidance there are software examples in a context past calcium signalling in significant fields: investigations of remoted cardiac myocytes and pink blood mobile similar examine. whereas the mobile cardiology part offers snapshots of yes calcium signalling points, the pink blood telephone half offers an summary from the practical identity of calcium-channels to an idea of physiological and pathophysiological relevance.

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Additional info for Calcium signalling: Approaches and Findings in the Heart and Blood

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Furthermore, the different calcium buffers play crucial roles, and other calcium transport proteins, such as inositol triphosphate (IP3)-receptors101,102, transient receptor potential (TRP)-channels103,104 and N-methyl-D-aspartate-(NMDA) receptors105, just to name a few, have a further modulatory function. The entirety of this modulation of the calcium signals in the heart is so complex that a comprehensive description would go beyond the scope of this summary. Therefore, the reader is referred to textbooks106,107 and recent reviews108-113.

132] Halperin, J. , Van Ha, T. & Tosteson, D. C. Voltage-activated cation permeability in high-potassium but not low-potassium red blood cells. American Journal of Physiology - Cell Physiology 258, 1169–1172 (1990). [135] Christophersen, P. & Bennekou, P. Evidence for a voltage-gated, non-selective cation channel in the human [136] [137] [138] [139] [140] [141] [142] [143] [144] [145] [146] [147] [148] [149] 11 red cell membrane. Biochimica et Biophysica Acta 1065, 103–106 (1991). Foller, M. et al.

157] Brini, M. & Carafoli, E. Calcium signalling: a historical account, recent developments and future perspectives. Cellular and Molecular Life Sciences 57, 354–370 (2000). -P. & Verkhratsky, A. Calcium signaling in physiology and pathophysiology. Acta Ppharmacologica Sinica 27, 767–772 (2006). [159] Knot, H. J. et al. Twenty years of calcium imaging: cell physiology to dye for. Molecular Intervention 5, 112– 127 (2005). [160] Bush, A. I. Kalzium Ist Nicht Alles. Neuron 65, 143–144 (2010). [161] Powell, T.

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Calcium signalling: Approaches and Findings in the Heart and Blood by Lars Kaestner


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