By Lia Angela Moulopoulos, Vassilis Koutoulidis
MRI presents the simplest technique of imaging the bone marrow at once and of non-invasively assessing its composition. general age-related bone marrow adjustments, adjustments with regards to purple marrow reconversion, and pathological bone marrow methods typically agree to definite styles that replicate the underlying marrow alterations and will be essentially famous on MR photographs. as well as traditional pulse sequences, complex MRI recommendations resembling Dynamic Contrast-Enhanced MRI and Diffusion-Weighted Imaging depict marrow alterations on the microvascular and mobile point respectively.
This ebook presents radiologists with in-depth details at the MRI appearances of ordinary, irregular and taken care of marrow following a established, pattern-based method. MRI findings for varied illnesses that have an effect on the bone marrow, really these of a malignant nature, are provided intimately. MRI trend attractiveness not just deals a scientific method of snapshot interpretation and prognosis but in addition has prognostic implications in regards to a few sickness entities. every one bankruptcy contains a wealth of top of the range photographs, including Key issues summarizing an important details.
In addition to radiologists, practitioners with an curiosity in hematology and oncology will locate this textbook-atlas to be a beneficial source for the most recent, clinically proper advances in bone marrow imaging.
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Additional info for Bone Marrow MRI: A Pattern-Based Approach
Dawson KL, Moore SG, Rowland JM (1992) Age-related changes in the pelvis: MR and anatomic findings. Radiology 183:47–51 5. Duda SH, Laniado M, Schick F et al (1995) Normal bone marrow in the sacrum of young adults: differences between sexes seen on chemical-shift MR imaging. Am J Roentgenol 164:935–940 6. Levine CD, Schweitzer ME, Ehrlich SM (1994) Pelvic marrow in adults. Skeletal Radiol 23:343–347 3 MRI of the Normal Bone Marrow: Anatomic Sites 7. Moore SG, Dawson KL (1990) Red and yellow marrow in the femur: age-related changes in appearance at MR imaging.
ADC measurements are not useful in distinguishing between infectious and malignant marrow lesions, since infectious spondylitis exhibits values within the malignant range . , b-values) used. In order for bone marrow DWI to gain wider acceptance, a consensus on these technical parameters should be reached. Standardization, especially concerning b-values, is mandatory for results among studies to be comparable. 2 Fig. 22 DWI of the normal bone marrow, young adult. Diffusion-weighted images with b-values 0, 150, 250, 500, and 750 s/mm2 (a) and ADC parameter map (b) of the lumbosacral spine of a healthy 24-year-old woman.
In order to reach a correct diagnosis, careful interpretation of the other pulse sequences and review of the patient’s history are required (Fig. 24). Lymphoproliferative disorders (leukemia, lymphoma, multiple myeloma) may manifest with a diffuse hypointense pattern. Hypointense diffuse bone marrow patterns may be homogeneous as in patients with leukemia or heterogeneous with superimposed focal areas of even lower signal intensity, a pattern commonly seen in patients with lymphoma; focal low-signal-intensity areas, against a background of diffusely hypointense marrow, may be related to denser aggregates of malignant cells (Fig.
Bone Marrow MRI: A Pattern-Based Approach by Lia Angela Moulopoulos, Vassilis Koutoulidis