By Alexander Sulakvelidze, Elizabeth Kutter
In keeping with the emergence of pathogenic micro organism that can't be taken care of with present antibiotics, many researchers are revisiting using bacteriophages, or phages, to struggle multidrug-resistant micro organism. Bacteriophages: Biology and functions presents unheard of, entire info on bacteriophages and their functions, equivalent to phage remedy. It deals concepts, media, and method interested by setting apart and dealing with healing phages. photos, line drawings, and electron micrographs of phages also are integrated. With its vast technique, this e-book is an invaluable reference for microbiologists, hematologists, and infectious affliction researchers.
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Extra info for Bacteriophages: Biology and Applications
This bacterium was selected because it grew well and was available from Carl Lindegren, one of Morgan’s students who had turned to work on microorganisms. Ellis’s work on the biology of bacteriophages attracted sufficient attention to be featured in a front-page story in the Los Angeles Times of April 30, 1938. At this time Ellis focused on the basic biology of the phage and its role as a model virus. Because Delbrück was not mentioned in this article, it is possible that he had not yet joined Ellis, or that his contributions to the project had not become noteworthy.
Independent functions of viral protein and nucleic acid in growth of bacteriophage, J Gen Physiol, 36, 39–56, 1952. , Growth and inheritance in bacteriophage, Carnegie Inst Wash Yearbook, 50, 195, 1951. D. , Genetic recombination between host-range and plaque-type mutants of bacteriophage in single bacterial cells, Genetics, 34, 44, 1949. Jacob, F. , Genetic regulatory mechanisms in the synthesis of proteins, J Mol Biol, 3, 318–356, 1961. , Electron microscopy of developing bacteriophage, in Phage and the Origins of Molecular Biology, J.
4. 5. 1. 2. 1. 2. 3. 3. 1. 2. 3. 4. 8. 1. 1. THE NATURE OF BACTERIOPHAGES As discussed throughout this book, bacteriophages are viruses that only infect bacteria. They are like complex spaceships (Fig. 1), each carrying its genome from one susceptible bacterial cell to another in which it can direct the production of more phages. Each phage particle (virion) contains its nucleic acid genome (DNA or RNA) enclosed in a protein or lipoprotein coat, or capsid; the combined nucleic acid and capsid form the nucleocapsid.
Bacteriophages: Biology and Applications by Alexander Sulakvelidze, Elizabeth Kutter